Institute of Physiology - Department of Physiological Genomics
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Content

Publications

A) Peer Reviewed Journals

B) Reviews and Articles in Books

C) Editor of Special Issues

D) Textbook Contributions

A) Peer Reviewed Journals

2017

Heimann G., Canhos L.L., Frik J., Jäger G., Lepko T., Ninkovic J., Götz M. and Sirko S. (2017) Changes in the Proliferative Program Limit Astrocyte Homeostasis in the Aged Post-Traumatic Murine Cerebral Cortex. Cerebral Cortex, 1-16

Falk S., Bugeon S., Ninkovic J., Pilz G.-A., Postiglione M.-P., Cremer H., Knoblich J.A. and Götz M. (2017) Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding. Neuron 93, 777-791. Highlighted by Vanderhaeghen P., Neuron doi: 10.1016/j.neuron.2017.02.015 and Recommended by Faculty of 1000

Gascón S., Ortega F. and Götz M. (2017) Transient Creb-mediated transcription is Key in direct neuronal reprogramming. Neurogenesis doi/full/10.1080/23262133.2017.1285383.

Supplie L., Düking T., Campbell G., Diaz F., Moraes C., Götz M., Hamprecht B., Mahad D., Boretius S., and Nave K.-A. (2017) Respiration-deficient astrocytes survive as glycolytic cells in vivo. Journal of Neuroscience 37, 4231-4242.

2016

Ramesh V.*, Bayam E.*, Cernilogar F.M., Bonapace I.M, Schulze M., Riemenschneider M.J., Schotta G. and Götz M. (2016) Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration.
Genes & Development 30, 2199-2212. IF:10.798

Falkner S.*, Grade S.*, Dimou L., Conzelmann K.-K., Tobias Bonhoeffer, Götz M.* and Hübener M.* (2016) Transplanted embryonic neurons integrate into adult neocortical circuits. Nature 539, 248-253. Highlighted by Grealish and Parmar, Cell Stem Cell 19, 679-680. IF 42.351

Köferle A., Worf K., Breunig C., Baumann V., Herrero J., Wiesbeck M., Hutter L.H., Götz M., Fuchs C., Beck S. and Stricker S.H. (2016) CORALINA: A universal method for the generation of gRNA libraries for CRISPR-based screening. BMC Genomics 17, DOI 10.1186.IF: 3.968

Garcia-Caceres C., Carmelo Q., Varela L, Gao Y., Gruber T., Legutko B., Jastroch M., Johansson P., Ninkovic J., Yi C-X., Le Thuc O., Szigeti-Buck K., Cai W., Meyer C.W., Pfluger P.T., Fernandez A.M., Luquet S., Woods S.C., Torres-Alemán I., Kahn C.R., Götz M., Horvath T.L. and Tschöp M.H. (2016) Astrocytic insulin signaling couples brain glucose uptake with nutrient availability. Cell 166, 867-80. IF: 32.242

Martínez M.A.M., Romero C.D.J., Fernández V., Cárdenas A., Götz M. and Borrell V. (2016) A restricted period for formation of Outer Subventricular Zone defined by Cdh1 and Trnp1 levels. Nature Communications 7, 1-15.IF:10.742

Gascón S.*, Murenu E.*, Masserdotti G., Ortega F., Russo G.L., Petrik D., Deshpande A., Heinrich C., Karow M., Robertson S.P., Schroeder T., Beckers J., Irmler M., Berndt C., Angeli J.P., Conrad M., Berninger B. and Götz M. (2016) Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming. Cell Stem Cell 18, 396-409. Highlighted by Quadrato et al., Cell Stem Cell 18, 297-299. IF: 22.268

2015

Lahiri S., Sun N., Solis-Mezarino V., Fedisch A., Ninkovic J., Feuchtinger A., Götz M., Walch A.K. and Imhof A. (2015) In situ detection of histone variants and modifications in mouse brain using imaging mass spectrometry. Proteomics 16, 437-447. IF: 3.807

Sirko S., Irmler M., Gascón S., Bek S., Schneider S., Dimou L., Obermann J., De Souza Paiva D., Poirier F., Beckers J., Hauck S.M., Barde Y.A. and Götz M. (2015) Astrocyte reactivity after brain injury - The role of galectins 1 and 3. Glia 63, 2340-2361. IF: 6.031

Kyrousi C., Arbi M., Pilz G.-A., Pefani D.E., Lalioti M.E., Ninkovic J., Götz M., Lygerou Z. and Taraviras S. (2015) Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche. Development 142, 3661-3674. IF: 6.462

Huettl R.-E., Eckstein S., Stahl T., Petricca S., Ninkovic J., Götz M. and Huber A. B. (2015) Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development. Developmental Biology, pii: S0012-1606(15)30051-8.IF: 3.547

Masserdotti G.*, Gillotin S.*, Sutor B., Drechsel D., Irmler M., Jørgensen H.F., Sass S., Theis F.J., Beckers J., Berninger B., Guillemot F.* and Götz M.* (2015) Transcriptional mechanisms of proneural factors and REST in regulating neuronal reprogramming of astrocytes. Cell Stem Cell 17, 74 – 88. Highlighted by Wang et al., Cell Stem Cell 17, 1-3. IF: 22.268

Barbosa J., Sanchez Gonzalez R., Di Giaimo R., Baumgart E.V., Theis, F.J., Götz M. and Ninkovic J. (2015) Live imaging of adult neural stem cell behavior in the intact and injured zebrafish brain. Science 348, 789 – 793. IF: 31.477

Calzolari F., Michel J., Baumgart E., Theis F., Götz M.* and Ninkovic J.* Fast clonal expansion and limited neural stem cell self-renewal in the adult subependymal zone. (2015). Nature Neuroscience, doi:10.1038/nn.3963.

Aida T., Yoshida J., Nomura M., Tanimura A., Lino Y., Soma M., Bai N., Ito Y., Cui W., Aizawa H., Yanagisawa M., Nagai T., Takata N., Tanaka K.F., Takayanagi R., Kano M., Götz M., Hirase H. and Tanaka K. (2015) Astroglial Glutamate Transporter Deficiency Increases Synaptic Excitability and Leads to Pathological Repetitive Behaviors in Mice. Neuropsychopharmacology, doi: 10.1038/npp.2015.26.

Bergami M., Masserdotti G., Temprana S.G., Motori E., Eriksson T.M., Göbel J., Yang S.M.,4 Conzelmann K-K., Schinder A.F., Götz M. and Berninger B. (2015) A Critical Period for Experience-Dependent Remodeling of Adult-Born Neuron Connectivity. Neuron 85, 710–717.

2014
Heinrich C., Bergami M., Gascon S., Lepier A., Viganó F., Dimou L., Sutor B., Berninger B. and Götz M. (2014). Sox2-mediated conversion of NG2 glia into induced neurons in the injured adult cerebral cortex. Stem Cell Reports 3, 1000-1014.

Beckervordersandforth R., Deshpande A., Schäffner I., Huttner H.B., Lepier A., Lie D.C., and Götz M. (2014) In vivo targeting of adult neural stem cells in the dentate gyrus by a split-Cre approach. Stem Cell Reports 2, 153-162.

Schmidt M.-T., Weinandy F., Wilsch-Bräuninger M., Huttner W.B., Cappello S., Götz M. (2014) The role of α-E-catenin in cerebral cortex development: radial glia specific effect on neuronal migration. Frontiers in Cellular Neuroscience 8, 215.

Agoston Z., Heine P., Brill M.S., Grebbin B.M., Hau A.-C., Kallenborn-Gerhardt W., Schramm J., Götz M., and Schulte D. (2014) Meis2 is a Pax6-cofactor in neurogenesis and dopaminergic periglomerular fate specification in the adult olfactory bulb. Development 141, 28-38.

2013
Motori E., Puyal J., Toni N., Ghanem A., Angeloni C., Malaguti M., Cantelli-Forti G., Berninger B., Conzelmann K.-K., Götz M., Winklhofer K., Hrelia S. and Bergami M. (2013) Inflammation-Induced Alteration of Astrocyte Mitochondrial Dynamics Requires Autophagy for Mitochondrial Network Maintenance. Cell Metabolism 18, 844-59.

Viganò F., Möbius W., Götz M. and Dimou L. (2013) Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain. Nature Neuroscience 16, 1370-1372.

Cappello S., Gray M.J., Badouel C., Lange S., Einsiedler M., Srour M., Chitayat D., Hamdan F.F., Jenkins Z.A., Morgan T., Preitner N., Uster T., Thomas J., Shannon P., Morrison V., Di Donato N., Van Maldergem L., Neuhann T., Newbury-Ecob R., Swinkells M., Terhal P., Wilson L.C., Zwijnenburg P.J.G., Sutherland-Smith A.J., Black M.A., Markie D., Michaud J.L., Simpson M.A., Mansour S., McNeill H., Götz M. and Robertson S.P. (2013) Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development. Nature Genetics 45, 1300-8. Highlighted by Faculty of 1000

Ninkovic J., Steiner-Mezzadri A., Jawerka M., Akinci U., Masserdotti G., Petricca S., Fischer J., von Holst A., Beckers J., Lie C.D., Petrik D., Miller E., Tang J., Wu J., Lefebvre V., Demmers J., Eisch A., Mezger D., Crabtree G., Irmler M., Poot R. and Götz M. (2013) The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network. Cell Stem Cell 13, 403-418. Highlighted by Faculty of 1000

Pilz G.-A., Shitamukai A., Reillo I., Pacary E., Schwausch J., Stahl R., Ninkovic J., Snippert H.J., Clevers H., Godinho L., Guillemot F., Borrell V., Matsuzaki F. and Götz M. (2013) Amplification of progenitors in the mammalian telencephalon includes a novel radial glial cell type. Nature Communications 4, 2125.

Robins S., Stewart I., McNay D., Taylor V., Giachino C., Goetz M., Ninkovic J., Briancon N., Maratos-Flier E., Flier J.S., Kokoeva M.V. and Placzek M. (2013) Alpha-tanycytes of the adult hypothalamic third ventricle include distinct populations of FGF-responsive neural progenitors. Nature Communications 4, 2049.

Stahl R., Walcher T., De Juan Romeo C., Pilz G.A., Cappello S., Irmler M., Sanz Anquela J.M., Beckers J., Blum R., Borrell V. and Götz M. (2013) Trnp1 regulates expansion and folding of the mammalian cerebral cortex by control of radial glial fate. Cell 153, 535-49. Highlighted by Nature, Science and Embo Journal.

Sirko S., Behrendt G., Johansson P., Tripathi P., Costa M., Bek S., Heinrich C., Tiedt S., Colak D., Dichgans M., Fischer I.R., Plesnila N., Staufenbiel M., Haass C., Snapyan M., Saghatelyan A., Tsai L.-H., Fischer A., Grobe K., Dimou L. and Götz M. (2013) Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog. Cell Stem Cell 12, 426-439. Highlighted in Embo reports

Bardehle S., Krüger M., Schwausch J., Ninkovic J., Clevers H., Snippert H.J., Buggenthin F., Theis F.J., Meyer-Luehmann M., Bechmann I., Dimou L. and Götz M. (2013) Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation. Nature Neuroscience 16, 580-6. Highlighted in Embo reports

Walcher T., Xie Q., Sun J., Irmler M., Beckers J., Öztürk T., Niessing D., Stoykova A., Cvekl A., Ninkovic J. and Götz M. (2013) Molecular mechanisms of coordinating neurogenesis and proliferation – functional dissection of the paired domain of Pax6. Development 140, 1123-36.

Johansson P.A., Irmler M., Acampora D., Beckers J., Simeone A. and Götz M. (2013) The transcription factor Otx2 regulates chroroid plexus development and function. Development 140, 1055-1066. Highlighted by Faculty of 1000

Behrendt G., Baer K., Buffo A., Curtis M.A., Faull R.L., Rees M.I., Götz M. and Dimou L. (2013) Dynamic changes in myelin aberration and oligodendrocyte generation in chronic amyloidosis in mice and men. Glia 61, 273-286.

Deshpande A., Bergami M., Ghanem A., Conzelmann K.K., Lepier A., Götz M. and Berninger B. (2013) Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb. PNAS 110(12), E1152-61.

Xie Q., Yang Y., Huang J., Ninkovic J., Walcher T, Wolf L., Vitenzon A., Zheng D., Götz M., Beebe D.C., Zavadil J., Cvekl A. (2013) Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain. PLOS One 8(1):e54507.

Decarolis N.A., Mechanic M., Petrik D., Carlton A., Ables J.L., Malhotra S., Bachoo R., Götz M., Lagace D.C. and Eisch A.J. (2013) In vivo contribution of nestin- and GLAST-lineage cells to adult hippocampal neurogenesis. Hippocampus Apr 4. doi: 10.1002/hipo.22130.

2012

Cappello S., Böhringer C.R.J., Bergami M., Conzelmann K.-K., Ghanem A., Tomassy G.S., Arlotta P., Mainardi M., Allegra M., Caleo M., van Hengel J., Brakebusch C., and Götz M. (2012) A radial glia specific role of RhoA in double-cortex formation. Neuron 73, 911-924.

Karow M., Sanchez R., Schichor C., Masserdotti G., Ortega F., Heinreich C., Gascon S., Khan M., Lie C., Dellavalle A., Cossu G., Goldbrunner R., Götz M.* and Berninger B.* (2012) Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells. Cell Stem Cell 11, 471-6.

Baumgart E.V., Barbosa J., Bally-Cuif L., Götz M. and Ninkovic J. (2012) Stab wound injury of the zebrafish telencephalon – a model for comparative analysis of reactive gliosis. Glia 60, 343-357.

Simon C., Lickert H., Götz M. and Dimou L. (2012) Sox10-iCreERT2: A Mouse Line to Inducibly Trace the Neural Crest and Oligodendrocyte Lineage. Genesis 50, 506-15.

Marinaro C., Pannese M., Weinandy F., Sessa A., Bergamaschi A., Taketo M.M., Broccoli V., Comi G., Götz M., Martino G. and Muzio L. (2012) Wnt signaling has opposing roles in the developing and the adult brain that are modulated by Hipk1. Cerebral Cortex 2415-27.

Saulnier A., Keruzore M, De Clercq S., Bar I., Moers V., Magnani D., Walcher T., Filippis C., Kricha S., Parlier D., Viviani L., Matson C.K., Nakagawa Y., Theil T., Götz M., Mallamaci A., Marine J.-C., Zarkower D. and Bellefroid E.J. (2012) The Doublesex Homolog Dmrt5 is Required for the Development of the Caudomedial Cerebral Cortex in Mammals. Cerebral Cortex 23, 2552-67.

Saab A.S., Neumeyer A., Jahn H.M., Cupido A., Simek A.A.M., Boele H.-J., Scheller A., Le Meur K., Götz M., Monyer H., Sprengel R., Rubio M.E., Deitmer J.W., De Zeeuw C.I. and Kirchhoff F. (2012) Bergmann Glial AMPA Receptors Are Required for Fine Motor Coordination. Science 337, 749-753.

Jafari M., Soerensen J., Bogdanovic R.M., Dimou L., Götz M. and Potschka H. (2012) Long-term genetic fate mapping of adult generated neurons in a mouse temporal lobe epilepsy model. Neurobiology of Disease 48, 454-463.

Ohlig S., Pickhinke U., Sirko S., Bandari S., Hoffmann D., Dreier R., Farshi P., Götz M. and Grobe K. (2012) An Emerging Role of Sonic hedgehog Shedding as a Modulator of Heparan sulfate Interactions. Journal of Biological Chemistry 287, 43708-19.

2011

Asami M., Pilz G.A., Ninkovic J., Godinho L., Schroeder T., Huttner W.B. and Götz M. (2011) The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex. Development 138, 5067-5078.

Robel S., Bardehle S., Lepier A., Brakebusch C. and Götz M. (2011) Genetic deletion of Cdc42 reveals a crucial role for astrocyte recruitment to the injury site in vitro and in vivo. Journal of Neuroscience 31, 12471-82.

Blum R., Heinrich C., Sanchez R., Lepier A., Gundelfinger E.D., Berninger B. and Götz M. (2011) Neuronal network formation from reprogrammed rat cortical glial cells. Cerebral cortex 21, 413-424.

Fischer J., Beckervordersandforth R., Tripathi P., Steiner-Mezzadri A., Ninkovic J. and Götz M. (2011) Prospective isolation of adult neural stem cells from the mouse subependymal zone. Nature Protocols 6, 1981-1989.

Simon C., Götz M. and Dimou L. (2011) Progenitors in the adult cerebral cortex – cell cycle properties and regulation by physiological stimuli and injury. Glia 59, 869-881.

Ortega F., Costa M.R., Simon-Ebert T., Schroeder T., Götz M. and Berninger B (2011) Using an adherent cell culture of the mouse subependymal zone to study the behavior of adult neural stem cells on a single cell level. Nature Protocols 6, 1847-1859.

Costa M.R., Ortega F., Brill M.S., Beckervordersandforth R., Petrone C., Schroeder T., Götz M. and Berninger B. (2011) Continuous live imaging of adult neural stem cell division and lineage progression in vitro. Development 138, 1057-1068. Highlighted by Faculty of 1000

Heinrich C., Gascón S., Masserdotti G., Lepier A., Sanchez R., Simon-Ebert T., Schroeder T., Götz M. and Berninger B. (2011) Generation of subtype specific neurons from postnatal astroglia of the mouse cerebral cortex. Nature Protocols 6, 214 - 228.

Gampe K., Brill M.S., Momma S., Götz M. and Zimmermann H. (2011) EGF induces CREB and ERK activation at the wall of the mouse lateral ventricles. Brain Research 1376, 31 - 41.

Winpenny E., Lebel-Potter M., Fernandez M.E., Brill M.S., Götz M., Guillemot F. and Raineteau O. (2011) Sequential generation of olfactory bulb glutamatergic neurons by Neurog2-expressing precursor cells. Neural Development 6, 12.

Rothenaigner I., Krecsmarik M., Hayes John A., Bahn B., Lepier A., Fortin G., Götz M., Jagasia R. and Bally-Cuif L. (2011) Clonal analysis by distinct viral vectors identifies bona fide neural stem cells in the adult zebrafish telencephalon and characterizes their division properties and fate. Development 138, 1459-1469.

2010

Beckervordersandforth R., Tripathi P., Ninkovic J., Bayam E., Lepier A., Stempfhuber B., Kirchhoff F., Hirrlinger J., Haslinger A., Chichung L. D., Beckers J., Yoder B., Irmler M. and Götz M. (2010) In vivo fate mapping and expression analysis reveals unique molecular hallmarks of prospectively isolated adult neural stem cells. Cell Stem Cell 7, 744-58. Highlighted by Faculty of 1000

Ninkovic J., Pinto L., Petricca S., Lepier A., Sun J., Rieger M.A., Schroeder T., Cvekl A., Favor J. and Götz M. (2010) The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin αA. Neuron 68, 682-694.

Jawerka M., Colak D., Dimou L., Spiller C., Lagger S., Montgomery R.L., Olson E.N., Wurst W., Göttlicher M. and Götz M. (2010) The specific role of histone deacetylase 2 in adult neurogenesis. Neuron Glia Biology 6, 93-107.

Heinrich C., Blum R., Tripathi P., Götz M.* and Berninger B.* (2010) Directing astroglia from the cerebral cortex into functional subtype-specific neurons. PLOS Biology 8(5):e1000373. Highlighted by Nature.

Kronenberg G., Gertz K., Cheung G., Buffo A., Kettenmann H., Götz M. and Endres M. (2010) Modulation of fate determinants Olig2 and Pax6 in resident glia evokes spiking neuroblasts in a model of mild brain ischemia. Stroke 41, 2944-2949.

Sirko S., von Holst A., Weber A., Wizenmann A., Theocaridis U., Götz M. and Faissner A. (2010) Chondroitin Sulfates are required for FGF-2-dependent proliferation and maintenance in neural stem cells and for EGF-dependent migration of their progeny. Stem Cells 28, 775-787.

Gajera C.R., Emich H., Lioubinski O., Christ A., Beckervordersandforth-Bonk R., Yoshikawa K., Bachmann S., Christensen E.I., Götz M., Kempermann G., Peterson A.S., Willnow T.E. and Hammes A. (2010) LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche. Journal of Cell Science 123, 1922-1930.

Mira H., Andreu Z., Suh H., Lie D.C., Jessberger S., Emeterio J.S., Hortigüela R., Marqués-Torrejón M.A., Nakashima K., Consiglio A., Colak D., Götz M., Fariñas I. and Gage F.H. (2010) Signalling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus. Cell Stem Cell 7, 78-89.

Lugert S., Basak O., Knuckles P., Haussler U., Fabel K., Götz M., Haas C.A., Kempermann G., Taylor V. and Giachino C. (2010), Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and ageing. Cell Stem Cell 6, 445-456.

Reddy-Alla S., Schmitt B., Birkenfeld J., Eulenburg V., Dutertre S., Böhringer C., Götz M., Betz H. and Papadopoulos T. (2010) PH-Domain driven targeting of collybistin but not Cdc42 activation is required for synaptic gephyrin clustering. European Journal of Neuroscience 31, 1173-1184.

Dames P., Puff R., Weise M., Parhofer K.G., Göke B., Götz M., Graw J., Favor J. and Lechner A. (2010) Relative roles of the different Pax6 domains for pancreatic alpha cell development. BMC Developmental Biology 10, 39.

2009

Pinto L., Drechsel D., Schmid M.-T., Ninkovic J., Irmler M., Brill M.S., Restani L., Gianfranceschi L., Cerri C., Weber S.N., Tarabykin V., Guillemot F., Beckers J., Zecevic N., Dehay C., Caleo M., Schorle H. and Götz M. (2009) AP2γ regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex. Nature Neuroscience 12, 1229-1237.

Brill M.S., Ninkovic J., Winpenny E., Hodge R.D., Ozen I., Yang R., Lepier A., Gascón S., Erdelyi F., Szabo G., Parras C., Guillemot F., Frotscher M., Berninger B., Hevner R.F., Raineteau O. and Götz M. (2009) Adult generation of glutamatergic olfactory bulb interneurons. Nature Neuroscience 12, 1524-1533. Highlighted by Faculty of 1000

Robel S., Mori T., Soubaa Z., Schlegel J., Sirko S., Faissner A., Goebbels S., Dimou L. and Götz M. (2009) Conditional deletion of b1 integrin in astroglia causes partial reactive gliosis. Glia 57, 1630-1647.

Costa M.R., Buchholz O., Schroeder T. and Götz M. (2009) Late origin of glia-restricted progenitors in the developing mouse cerebral cortex. Cerebral Cortex 19, 135-43.

Snapyan M., Lemasson M., Brill M.S., Blais M., Massouh M., Ninkovic J., Gravel C., Berthod F., Götz M., Barker P.A., Parent A. and Saghatelyan A. (2009) Vasculature guides migrating neuronal precursors in the adult mammalian forebrain via BDNF signaling. Journal of Neuroscience 29, 4172-4188. Faculty of 1000 ‘Must read’

Hirschberg A., Deng S., Korostylev A., Paldy E., Costa M.R., Worzfeld T., Vodrazka P., Wizenmann A., Götz M., Offermans S. and Kuner R. (2009) Gene deletion mutants reveal a role for semaphoring receptors of the Plexin-B family in mechanisms underlying corticogenesis. Molecular and Cellular Biology 30, 764-780.

Rivera F.J., Siebzehnrubl F.A., Kandasamy M., Couillard-Despres S., Caioni M., Poehler A.-M., Berninger B., Sandner B., Bogdahn U., Götz M., Bluemcke I., Weidner N. and Aigner L. (2009) Mesenchymal stem cells promote oligodendroglial differentiation in hippocampal slice cultures. Cellular Physiology and Biochemistry 24, 317-324.

2008

Buffo A., Rite I., Tripathi P., Lepier A., Colak D., Horn A.-P., Mori T. and Götz M. (2008) Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain. PNAS 105, 3581-3586.

Costa M.R., Wen G., Lepier A., Schroeder T. and Götz M. (2008) Par complex proteins promote self-renewing progenitor divisions in the developing mouse cerebral cortex. Development 135, 11-22. Highlighted by Faculty of 1000

Dimou L., Simon C., Kirchhoff F., Takebayashi H. and Götz M. (2008) Progeny of Olig2-expressing progenitors in the grey and white matter of the adult mouse cerebral cortex. Journal of Neuroscience 28, 10434-10442.

Brill M., Snapyan M., Wohlform H., Ninkovic J., Jawerka M., Mastick G.S., Ashery-Padan R., Saghatelyan A., Berninger B. and Götz M. (2008) A Dlx2- and Pax6-dependent transcriptional code for periglomerular neuron specification in the adult olfactory bulb. Journal of Neuroscience 28, 6439-6452.

Colak D., Mori T., Brill M.S., Pfeifer A., Falk S., Deng C., Monteiro R., Mummery C., Sommer L. and Götz M. (2008) Adult Neurogenesis Requires Smad4-Mediated Bone Morphogenic Protein Signaling in Stem Cells. Journal of Neuroscience 28, 434-446.

Pinto L., Mader M.T., Irmler M., Gentilini M., Santoni F., Drechsel D., Blum R., Stahl R., Bulfone A., Malatesta P., Beckers J. and Götz M. (2008) Prospective isolation of functionally distinct radial glial subtypes-Lineage and transcriptome analysis. Molecular and Cellular Neuroscience 38, 15-42.

Bergami M., Rimondini R., Sauri S., Blum R., Götz M. and Canossa M. (2008) Deletion of TrkB in adult progenitors alters newborn neurons integration into hippocampal circuits and increases anxiety like behaviour. PNAS 105, 15570-15575. Highlighted by Faculty of 1000

Falk S., Wurdak H., Ittner L.M., Ille F., Sumara G., Schmid M.-T., Draganova K., Lang K.S., Paratore C., Leveen P., Suter U., Karlsson S., Born W., Ricci R., Götz M. and Sommer L. (2008) Brain area-specific effect of TGFb signaling on WNT-dependent neural stem cell expansion. Cell Stem Cell 2, 472-483.

Bonilla S., Hall A.C., Pinto L., Attardo A., Götz M., Huttner W.B. and Arenas E. (2008) Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors. Glia 56, 809-820.

2007

Nikoletopoulou V., Plachta N., Allen N., Pinto L., Götz M. and Barde Y.-A. (2007)

Neurotrophin Receptor-Mediated Death of Misspecified Neurons Generated from Embryonic Stem Cells Lacking Pax6. Cell Stem Cell 1, 529-540.

Ma L., Cantrup R., Varrault A., Colak D., Klenin N., Götz M., McFarlane S., Journot L. and Schuurmans C. (2007) Zac1 functions through TGFb to negatively regulate cell number in the developing retina. Neural Development 8, 2-11.

Sirko S., von Holst A., Wizenmann A., Götz M. and Faissner A. (2007) Chondroitin sulfate glycosaminoglycans control proliferation, radial glia cell differentiation and neurogenesis in neural stem/progenitor cells. Development 134, 2727-2738.

Costa M.R., Kessaris N., Richardson W.D., Götz M. and Hedin-Pereira C. (2007) The marginal zone/layer I as a novel niche for neurogenesis and gliogenesis in developing cerebral cortex. Journal of Neuroscience 27, 11376-11388.

Ninkovic J., Mori T. and Götz M. (2007) Distinct modes of neuron addition in adult mouse neurogenesis. Journal of Neuroscience 27, 10906-10911.

Berninger B., Costa M.R., Koch U., Schroeder T., Sutor B., Grothe B. and Götz M. (2007) Functional properties of neurons derived from in-vitro reprogrammed postnatal astroglia. Journal of Neuroscience 27, 8654-8664.

Berninger B., Guillemot F. and Götz M. (2007) Directing neurotransmitter identity of neurons derived from expanded adult neural stem cells. European Journal of Neuroscience. 25, 2581-2590.

Holm P.C., Mader M.T., Haubst N., Wizenmann A., Sigvardsson M. and Götz M. (2007) Loss- and gain-of-function analyses reveal targets of Pax6 in the developing mouse telencephalon. Molecular and Cellular Neuroscience 34, 99-119.

2006

Cappello S., Attardo A., Wu X., Iwasato T., Itohara S., Wilsch-Braeuninger M., Eiken H.M., Rieger M.A., Schroeder T.T., Huttner W., Brakebusch C. and Götz M. (2006) The Rho-GTPase cdc42 regulates cortical precursor fate at the apical surface. Nature Neuroscience 9, 1099-1107. Highlighted by Faculty of 1000

Haubst N., Georges-Labouesse E., DeArcangelis A., Mayer U. and Götz M. (2006) Basement membrane attachment is dispensable for radial glial cell fate and proliferation, but affects positioning of neuronal subtypes. Development 133, 3245-3254.

Mori T., Tanaka K., Buffo A., Wurst W., Kühn R. and Götz M. (2006) Inducible gene deletion in astroglia and radial glia – a valuable tool for functional and lineage analysis. Glia 54, 21-31.

Adolf B., Chapouton P., Lam C.S., Topp S., Tannhäuser B., Strähle U., Götz M. and Bally-Cuif L. (2006) Conserved and acquired features of adult neurogenesis in the zebrafish telencephalon. Developmental Biology 295, 278-293.

Von Frowein J., Wizenmann A. and Götz M. (2006) The transcription factors Emx1 and Emx2 suppress choroid plexus development and promote neuroepithelial cell fate. Developmental Biology 296, 239-252.

Stricker S.H., Meiri K. and Götz M. (2006) P-GAP43 is enriched in horizontal cell divisions throughout rat cortical development. Cerebral Cortex 16, 121-131.

2005 - 2000

Buffo A., Vosko M., Ertürk D., Hamann G., Jucker M., Rowitch D. and Götz M. (2005) Expression pattern of the transcription factor Olig2 in response to brain injuries - implications for neuronal repair. PNAS 102, 18183-18188. Highlighted by Faculty of 1000

Hack M., Saghatelyan A., de Chevigny A., Lledo P.-M. and Götz M. (2005) Neuronal fate determinants of adult olfactory bulb neurogenesis. Nature Neuroscience 8, 865-872.

Haubst N., Berger J., Radjendirane V., Graw J., Favor J., Saunders G.F., Stoykova A. and Götz M. (2004) Molecular dissection of Pax6 function: the specific roles of the paired and homeodomain in brain development. Development 131, 6131-6140.

Nieto M., Monuki E.S., Tang H., Imitola J., Haubst N., Khoury S., Cunningham J., Götz M. and Walsh C.A. (2004) Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex. Journal of Comparative Neurology 479, 168-180.

Koutmani Y., Hurel C., Patsavoudi E., Hack M., Götz M., Thomaidou D. and Matsas R. (2004) BM88 is an early marker of proliferating precursor cells that will differentiate into the neuronal lineage. European Journal of Neuroscience 20, 2509-2523.

Bibel M., Richter J., Schrenk K., Tucker K.L., Staiger V., Korte M., Götz M. and Barde Y.-A. (2004) Differentiation of mouse embryonic stem cells into a defined neuronal lineage. Nature Neuroscience 7, 1003-1009.

Hack M.A., Sugimori M., Lundberg C., Nakafuku M. and Götz M. (2004) Regionalization and fate specification in neurospheres: the role of Olig2 and Pax6. Molecular and Cellular Neuroscience 25, 664-678.

Hartfuss E., Förster E., Bock H.H., Hack M.A., Leprince P., Luque J.M., Herz J., Frotscher M. and Götz M. (2003) Reelin signalling directly affects radial glia morphology and biochemical maturation. Development 130, 4597-609.

Stoykova A., Hatano O. and Götz M. (2003) Increase of reelin-positive cells in the Pax6-mutant mouse cortex. Cerebral Cortex 13, 560-571.

Malatesta P., Hartfuss E., Hack M.A., Klinkert W., Kirchhoff F., Kettenmann H. and Götz M. (2003) Neuronal or glial progeny: regional differences in radial glial fate. Neuron 37, 751-764. Highlighted by Faculty of 1000

Heins N., Malatesta P., Cecconi F., Nakafuku M., Tucker K.L., Hack M.A., Chapouton P., Barde Y. and Götz M. (2002) Glial cells generate neurons: the role of the transcription factor Pax6. Nature Neuroscience 5, 308-315.

von Frowein J., Campbell K. and Götz M. (2002) Expression of Ngn1, Ngn2, Cash1, Gsh2 and Sfrp1 in the developing chick telencephalon. Mechanisms of Development 110, 249-252.

Chapouton P., Schuurmans C., Guillemot F., and Götz M. (2001) The transcription factor Neurogenin 2 restricts cortical cell migration in the developing mouse telencephalon. Development 128, 5149-5159.

Heins N., Cremisi F., Malatesta P., Gangiemi R.M.R., Corte G., Price J., Goudreau G., Gruss P. and Götz M. (2001) Emx2 promotes symmetric cell divisions and a multipotential fate in precursors from the cerebral cortex. Molecular and Cellular Neuroscience 18, 485-502.

Hartfuss E., Galli R., Heins N. and Götz M. (2001) Characterization of CNS precursor subtypes and radial glia. Developmental Biology 229, 15-30.

Malatesta P., Götz M., Barsacchi G., Tirone F., Price J., Zoncu R. and Cremisi F. (2000) PC3 overexpression affects the pattern of cell division of rat cortical precursors. Mechanisms of Development 90, 17-28.

Malatesta P., Hartfuss E. and Götz M. (2000) Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage. Development 127, 5253-5263.

2000 - 1990

Chapouton P., Gärtner A. and Götz M. (1999) The role of Pax6 in restricting cell migration between developing cortex and basal ganglia. Development 126, 5569-5579.

Götz M., Stoykova A. and Gruss P. (1998) Pax6 controls radial glia differentiation in the cerebral cortex. Neuron 21, 1031-1044.

Stoykova A., Götz M., Gruss P. and Price J. (1997) Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain. Development 124, 3765-3777.

Götz M., Bolz J., Joester A. and Faissner A. (1997) Tenascin-C synthesis and influence on axonal growth during rat cortical development. European.Journal of Neuroscience 9, 496-506.

Henke-Fahle S., Mann F., Götz M., Wild K. and Bolz J. (1996) A dual action of a carbohydrate epitope on afferent and efferent axons in cortical development. Journal of Neuroscience. 16, 4195-4206.

Götz M., Wizenmann A., Reinhardt S., Lumsden A. and Price J. (1996) Selective adhesion of cells from different telencephalic regions. Neuron 16, 551-564.

Hübener M., Götz M., Klostermann S. and Bolz J. (1995) Guidance of thalamocortical axons by growth-promoting molecules in developing rat cerebral cortex. European.Journal of Neuroscience 7, 1963-1972.

Götz M., Williams B.P., Bolz J. and Price J. (1995) The specification of neuronal fate: a common precursor for neurotransmitter subtypes in the rat cerebral cortex in vitro. European Journal of Neuroscience 7, 889-898.

Götz M. and Bolz J. (1994) Differentiation of transmitter phenotypes in rat cerebral cortex. European.Journal of Neuroscience 6, 18-32.

Götz M., Novak N., Bastmeyer M. and Bolz J. (1992) Membrane bound molecules in rat cerebral cortex regulate thalamic innervation. Development 116, 507-519.

Götz M. and Bolz J. (1992) Formation and preservation of cortical layers in slice cultures. Journal of Neurobiology 23, 783-802.

Bolz J., Novak N., Götz M. and Bonhoeffer T. (1990). Formation of target-specific neuronal projections in organotypic slice cultures from rat visual cortex. Nature 346, 359-362.

Before 1990

Götz M. and Bolz J. (1989) Development of vasoactive intestinal polypeptide (VIP)-containing neurons in organotypic slice cultures from rat visual cortex. Neuroscience Letters 107, 6-11.

(*equal co-senior authorship)

B) Reviews and Articles in Books

Masserdotti G., Gascón S. and Götz M. (2016) Direct neuronal reprogramming: learning from and for development. Development 143, 2494-2510.

Götz M., Nakafuku M. and Petrik D. (2015) Neurogenesis in the Developing and Adult Brain—Similarities and Key Differences. CSH Perspectives, 1-23.

Götz M., Sirko S., Beckers J. and Irmler M. (2015) Reactive Astrocytes as neural stem or progenitor cells – in vivo lineage, in vitro potential, and genome-wide expression analysis. Glia 63,1452–1468.

Taverna E., Götz M., Huttner A.B. (2014) The cell biology of neurogenesis: Toward an understanding of the development and evolution of the neocortex. Annual Review of Cell and Developmental Biology 30, 465 – 502.

Ninkovic N. and Götz M. (2014) A time and place for understanding neural stem cell specification. Developmental Cell 30, 114-115.

Borrell V. and Götz M. (2014) Role of radial glial cells in cerebral cortex folding. Current Opinion in Neurobiology 27, 39-46.

Dimou, L. and Götz M. (2013) Glial cells as stem and progenitor cells. Physiological Reviews, in review.

Ninkovic, J. and Götz M. (2013) Fate specification in the adult brain - lessons for eliciting neurogenesis from glial cells. Bioassays, Ed. P.Tam.

Dimou, L. and Götz M. (2012) Shaping barrels: activity moves NG2+ glia. Nature Neuroscience 15, 1176 – 1178.

Sirko, S. and Götz M. (2012) Potential of glial cells. Stem Cells Handbook, 2nd ed. Ed..

Robel, S., Berninger, B. and Götz M. (2011) The stem cell potential of glia – lessons from reactive gliosis. Nature Reviews Neuroscience 12, 88-104.

Weinandy, F., Ninkovic, J. and Götz M. (2011) Restrictions in time and space – new insights into generation of specific neuronal subtypes in the adult mammalian brain. European Journal of Neuroscience 33, 1045 – 1054.

Götz M. (2010) Making glutamatergic neurons from GABAergic progenitors. Nature Neuroscience 13, 1308 - 1309.

Johansson P.A., Cappello S. and Götz M. (2010) Stem cell niches during development – lessons from the cerebral cortex. Current Opinion in Neurobiology 20, 1-8.

Costa M.R., Götz M. and Berninger B. (2010) What determines neurogenic competence in glia? Brain Research Reviews. 63, 47-59.

Lie C. and Götz M. (2007) Adult neurogenesis – similarities and differences in stem cell fate, proliferation, migration and differentiation in distinct forebrain regions. Cold Spring Harbour Series.

Pinto L. and Götz M. (2007) Radial glial cell heterogeneity – The source of diverse progeny in the CNS. Progress in Neurobiology 83, 2-23.

Ninkovic J. and Götz M. (2007) Signalling in adult neurogenesis: from stem cell niche to neuronal networks. Current Opinion in Neurobiology 17, 338-344.

Stricker S.H. and Götz M. (2006) Go with the flow: signalling from the ventricle directs neuroblast migration. Nature Neuroscience 9, 470-472.

Haubst N., Favor J. and Götz M. (2006) The role of Pax6 in the nervous system in development and adulthood: master control regulator or modular function? In Transcription factors in Development. Ed. Thiel, Wiley Press.

Berninger B., Hack M.A. and Götz M. (2006) Neural stem cells: on where they hide, in which disguise, and how we may lure them out. Handbook of Experimental. Pharmacology 174, 319-360.

Mori T., Buffo A. and Götz M. (2005) The novel roles of glial cells revisited: The contribution of radial glia and astrocytes to neurogenesis. Current Topics in Developmental Biology 69, 67-99.

Götz M. and Huttner W.B. (2005) The cell biology of neurogenesis. Nature Reviews Molecular Cell Biology 6, 777-788.

Götz M. and Sommer L. (2005) Cortical development: the art of generating cell diversity. Development 132, 3325-3332.

Götz M. and Barde Y.-A. (2005) Radial glial cells: defined and major intermediates between embryonic stem cells and CNS neurons. Neuron 46, 369-372.

Götz M. (2003) Doublecortin finds its place. Nature Neuroscience 6, 1245-1247.

Kriegstein A. and Götz M. (2003) Radial glia diversity: a matter of cell fate. Glia 43, 37-43.

Götz M. (2003) Glial cells generate neurons – master control within CNS regions. The Neuroscientist 9, 379-397.

Götz M. (2003) Brain development: Glial cells generate neurons – implications for neuropsychiatric disorders. In: Disorders of Brain and Mind II, Eds. M. Ron, T. Robbins. Cambridge University Press.

Campbell K. and Götz M. (2002) Radial glia: Multipurpose cells for vertebrate brain development. Trend in Neurosciences 25, 235-238.

Götz M., Hartfuss E. and Malatesta P. (2002) Radial glial cells as neuronal precursors - a new perspective on the correlation of morphology and lineage restriction in the developing cerebral cortex of mice. Brain Research Bulletin 57, 777-788.

Götz M. (2001) Gliazellen bilden Nervenzellen – Radiale Glia als Stammzellen des ZNS von Vertebraten. Neuroforum 01/2001, 3-10.

Götz M. (1999) Cerebral Cortex development. Encyclopedia of Life Sciences, Nature Publishing Group, London, www.els.net.

Götz M. (1998) Transmitting transmitter phenotypes. Perspectives of Developmental Neurobiology 5, 145-157.

Götz M. (1998) How are neurons specified: master or positional control? Trends in Neurosciences 21, 135-136.

Götz M., Stoykova A., Wizenmann A., Lumsden A., Gruss P. and Price J. (1997) How to become the right neuron at the right place: neuronal fate and positional specification in the developing forebrain. In: Molecular basis of axon growth and nerve pattern formation, Taniguchi Symposia on Brain Sciences 20. Ed. H. Fujisawa. pp.37-51.

Roberts G.W., Royston M.C. and Götz M. (1995) Pathology of cortical development and neuropsychiatric disorders. In: Development of the Cerebral Cortex, Ciba Foundation Symposium 193. Eds. Bock, G.R. and G. Cardew, Wiley & Sons, Chichester; p. 296-316.

Price J., Williams B.P. and Götz M. (1995) The generation of cellular diversity in the cerebral cortex. In: Development of the Cerebral Cortex, Ciba Foundation Symposium 193. Eds. Bock, G.R. and G. Cardew, Wiley & Sons, Chichester; p. 71-79.

Götz M. (1995) Getting there and being there in the cerebral cortex. Experientia 5, 359-369

Price J., Grove E., Williams B., Lavachev I., McNaugthon L. and Götz M. (1994) Labelling neural precursor cells with retroviruses. Gene Therapy 1, 4-5.

Götz M. and Price J. (1994) Cell fate and axonal projections from the cerebral cortex. Seminars in Cell and Developmental.Biology 5, 359-369.

Bolz J., Götz M., Hübener M., and Novak N. (1993) Reconstructing cortical connections in a dish. Trends in Neurosciences 16, 310-316.

Götz M. (1992) Über Keime. Zu einer Biologie der Ursachen. In Schmutz und Sauberkeit. Wasser. Schwabe &Co. AG, Basel, 225-240.

Bolz J. and Götz M. (1992) Mechanisms to establish specific thalamocortical connections in the developing brain. In Development of the central nervous system in vertebrates S.C. Sharma and A.M. Goffinet, eds. pp. 173-187, Plenum Press, New York.

C) Editor of Special Issues

Glia, 63, 2015. Editorial: p. 1288–1290

Current Opinion in Neurobiology, 13 (1), 2003. Editorial: p.3-7.

Glia, 43 (1), 2003. Editorial: p. 1-3.

D) Textbook Contribution

Radial glial cells, in: Neuroglia, 3rd edition, Editors: Kettenmann and Ransom, Oxford University Press, 2012

Biology and Function of Glial Cells, in: Neuroscience, Ed. G. Galizia and PM Lledo, Springer Verlag, in press


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