- Koch Group

Retinal plasticity

Major Research Interests

Retinal Function – Degeneration – Remodeling – Gene Therapy and Repair

Our work focuses on physiological and pathophysiological aspects of information processing in the retina as well as the restoration of vision by gene therapy. To address these topics we develop and analyze genetically engineered mouse models for human retinal diseases like retinitis pigmentosa (RP), a neurodegenerative disease and the most common cause of inherited blindness. Using our RP mouse lines, we combine various in vitro and in vivo techniques to characterize structural and functional changes of the retinal network and to test potential treatments. Our work contributed to the understanding of retinal degeneration, remodeling and restoration. Our current research projects aim to elucidate the mechanisms underlying retinal plasticity and to develop a critical knowledge for designing strategies to rescue vision. My group allows highly motivated individuals to be creative in an interactive and stimulating environment. Please contact us to learn more.

Dr. Susanne F. Koch