Institute of Physiology - Department of Physiological Genomics

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Stricker Group

The research aim of the Stricker lab is to investigate, which mechanisms ensure that cells do not change identity during the lifetime and how we can manipulate those to freely convert cell fates. We employ a wide range of CRISPR methods to test in vitro and in vivo, which epigenetic marks and gene activities have functional relevance in mediating cell identity or disease phenotypes in the brain.